The National Osteoporosis Society developed national clinical guidelines on the management of vitamin D deficiency in adult patients with, or at risk of developing, bone disease. These guidelines were revised in 2018.
Now named The Royal Osteoporosis Society as of March 2019, the work continues to raise awareness of the disease and to manage patients in the best possible way.
When treating vitamin D deficiency, oral vitamin D3 is recommended as the vitamin D preparation of choice and where rapid correction of vitamin D deficiency is required, the recommended treatment regimen is based on fixed loading doses followed by regular maintenance therapy
Loading regimens for treatment of vitamin D deficiency up to a total of approximately 300,000 IU may be given either as weekly or daily split doses
Maintenance regimens may be considered after loading, given either daily or intermittently at a higher equivalent dose